Thy1 Rat Monoclonal Antibody [Clone ID: G7]

Specifications

Product Data
Clone Name	G7
Applications	FC, FN, IHC
Recommend Dilution	Flow Cytometry. (Ref.1,10) Immunohistochemistry (Acetone-Fixed, Frozen Sections). (Ref.10) In vitro T Cell Activation. (Ref.1,5,6,9) Induction of apoptosis.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	This antibody recognises Thy-1.1 and Thy-1.2 alloantigens (Thy-1 epitope region A). MAb G7 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. (Ref.1,5-7). It has also been reported to promote apoptosis of thymocytes and CTL clones (Ref.4,7) and to mediate adhesion of thymocytes to thymic stroma. (Ref.8)
Formulation	100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	thymus cell antigen 1, theta
Database Link	Entrez Gene 21838 Mouse UniProt ID P01831
Background	CD90/Thy-1, a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. (Ref.1-4) It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes and neurons of all mouse strains. (Ref.1,2)
Synonyms	Thy-1, THY1, CDw90
Reference Data

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