Cd24a Rat Monoclonal Antibody [Clone ID: 30-F1]

Specifications

Product Data
Clone Name	30-F1
Applications	FC, IP
Recommend Dilution	Flow Cytometry and Cell Sorting. (Ref.3,4,7-10) Immunoprecipitation. (Ref.3)
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	This antibody recognises CD24/Heat Stable Antigen (HSA).
Formulation	100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD24a antigen
Database Link	Entrez Gene 12484 Mouse UniProt ID P24807
Background	CD24 (also known as heat stable antigen) is a phosphatidylinositol linked cell surface glycoprotein with a polypeptide core of 30 amino acids and high carbohydrate content. The apparent molecular mass of the two forms of CD24 purified from a mouse lymphoma cell line appear to be in the range of 40-60 and 23-30 kDa. CD24 is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+ CD8+ CD24+ thymocytes to either CD4+ CD8- CD24- or CD4- CD8+ CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. CD24 is also a positive marker of pancreatic cancer.
Synonyms	X62 heat stable antigen, HSA
Reference Data

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