CD8 Mouse Monoclonal Antibody [Clone ID: CT-8]
CAT#: AM08116BT-N
CD8 mouse monoclonal antibody, clone CT-8, Biotin
Conjugation: Unconjugated FITC PE
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CNY 5,841.00
Cited in 3 publications. |
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Specifications
Product Data | |
Clone Name | CT-8 |
Applications | FC |
Recommend Dilution | Flow Cytometry (≤ 1 µg/106 cells): Identification and enumeration of CD8+cells. (Ref.2) |
Reactivity | Chicken |
Host | Mouse |
Clonality | Monoclonal |
Specificity | This antibody recognizes alpha chain (34-kDa) of Chicken CD8. |
Formulation | PBS containing 0.09% Sodium Azide as preservative. Label: Biotin State: Liquid purified Ig fraction. |
Concentration | lot specific |
Conjugation | Biotin |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
Database Link | |
Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 is expressed on most thymocytes and approximately 1/3 of peripheral blood T cells in humans. CD8 alpha/beta heterodimers are expressed only on TCR alpha/beta T cells, whereas CD8 alpha homodimers can be expressed on alpha/beta and gamma/delta T cells and some NK cells in humans. The pattern of expression in other species has not been well documented. |
Synonyms | CD8 alpha chain, CD8A, MAL |
Reference Data |
Citations (3)
The use of this Antibodies has been cited in the following citations: |
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Clinical and pathological investigation of patients with severe COVID-19
,null,
JCI Insight
,PubMed ID 32427582
[CD8A]
|
Association Between Intra-Tumoral Immune Response and Programmed Death Ligand 1 (PD-L1) in Gastric Cancer
,null,
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
,PubMed ID 31519868
[CD8A]
|
N-propionyl-4-S-cysteaminylphenol induces apoptosis in B16F1 cells and mediates tumor-specific T-cell immune responses in a mouse melanoma model.
,null,
Journal of dermatological science
,PubMed ID 22622238
[CD8A]
|
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