CD71 (TFRC) Mouse Monoclonal Antibody [Clone ID: RVS10]

CAT#: AM08163LE-N

CD71 (TFRC) mouse monoclonal antibody, clone RVS10, Low Endotoxin



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CNY 5,984.00


货期*
4周

规格
    • 500 ug

Product images

Specifications

Product Data
Clone Name RVS10
Applications FC
Recommend Dilution Flow Cytometry.
Reactivity Human
Host Mouse
Clonality Monoclonal
Specificity This antibody is directed against the Human Transferrin Receptor (CD71).
Formulation PBS without preservatives.
State: Low Endotoxin
State: Liquid purified Ig fraction.
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store the antibody undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Gene Name transferrin receptor
Background The Transferrin Receptor has been structurally characterized as a sulfide bound dimer of identical glycoprotein subunits of 95 kDa. The transferrin receptor is not present on resting blood lymphocytes. On PBL, the receptor appears after activation. The expression of transferrin receptor is coordinately regulated with cell growth. Present on T and B cell lines. The soluble (or serum) transferrin receptor (sTfR) is a circulating truncated form of the membrane receptor protein; it is an 85 kDa glycoprotein forming in serum a 320 kDa complex with diferric transferrin. The most important clinical use of the sTfR determination is in the differential diagnosis between iron deficiency anaemia and the anaemia of chronic disease.
CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin. (Ref.1-4)
Synonyms TfR1, p90, Transferrin receptor protein 1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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