TDP1 Mouse Monoclonal Antibody [Clone ID: AT1F2]
CAT#: AM09086PU-N
TDP1 mouse monoclonal antibody, clone AT1F2, Purified
Size: 50 ul
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CNY 6,620.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | AT1F2 |
Applications | ELISA, IHC, WB |
Recommend Dilution | ELISA. Western blot: 1/1,000-1/2,000. Immunohistochemistry on Paraffin Sections: 5 µg/ml. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Recombinant Human TDP1 (1-298 aa) purified from E. coli |
Specificity | The antibody recognizes Human TDP1. Other species not tested. |
Formulation | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein G |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | tyrosyl-DNA phosphodiesterase 1 |
Database Link | |
Background | Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that catalyzes the hydrolysis of a phophodiester bond between a tyrosine residue and a DNA 3' phosphate. This protein is a member of the phospholipase D (PLD) superfamily and contains two PLD phosphodiesterase domains. Mutations in TDP1 are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1) by interfering with DNA transcription or by inducting apoptosis in postmitotic neurons. |
Synonyms | Tyrosyl-DNA phosphodiesterase 1 |
Reference Data | |
Protein Families | Druggable Genome |
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