Helicobacter pylori (CagA Protein) Mouse Monoclonal Antibody [Clone ID: 3C1]

Specifications

Product Data
Clone Name	3C1
Applications	ELISA
Recommend Dilution	ELISA: HP CagA antibody (Clone 3C1) can be used as Detection antibody. In Sandwich ELISA, anti-HP CagA antibody clone 10E9 (Cat#AM09221PU-N) and anti-HP CagA antibody clone 5H10 (Cat#AM09222PU-N) coated wells match with HRP conjugated clone 3C1 to detect the recombinant antigen. Application of Clone 3C1 in Detection of CagA containing HP strain was not evaluated.
Reactivity	Helicobacter pylori
Host	Mouse
Clonality	Monoclonal
Immunogen	A highly immunogenic 32Kd CagA fragment, recombinant.
Specificity	This antibody is raised against the H. pylori cytotoxin associated gene A protein (CagA). Reacts with the 32Kd recombinant Helicobacter pylori CagA. Cross reaction with other proteins has not been found.
Formulation	0.01M PBS, pH 7.0 without preservatives. State: Aff - Purified State: Lyophilized purified Ig fraction.
Reconstitution Method	Restore with Double distillated water to adjust the final concentration to 1.0 mg/ml.
Purification	Affinity Chromatography on Protein G.
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Background	Helicobacter pylori strains is known to exhibit a significant degree of diversity. The great variability in the H. pylori genome may explain why not all infected individuals suffer from ulcer. Some H. pylori strains contain particular pathogenic genes such as cytokine associated gene A (CagA), while others lack these genes. The CagA protein of H. pylori has been found to be associated with more severe clinical manifestations, such as ulcer disease and gastric cancer. Thus, discrimination between potentially virulent strains may be relevant.
Synonyms	H. pylori
Reference Data

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