KAT2A Mouse Monoclonal Antibody [Clone ID: AT3G13]

Specifications

Product Data
Clone Name	AT3G13
Applications	ELISA, IF, WB
Recommend Dilution	ELISA. Western blot (1:250 - 1:1000). Immunofluorescence (1:250 - 1:500).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human GCN5L2 (411-837aa) purified from E. coli
Specificity	The antibody recognizes human KAT2A (GCN5L2). Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	lysine acetyltransferase 2A
Database Link	Entrez Gene 2648 Human UniProt ID Q92830
Background	GCN5L2, as known as GCN5 and KAT2A is the use of immunoprecipitated GCN5L2 for acetylation to provide the additional components important for acetylation. GCN5L2 can be one of the potential enzymes involved in acetylation in vivo. GCN5L2 is expressed predominantly in the embryo and newborn and is essential for normal embryonic development. Therefore, GCN5L2 appears to be important for differentiation of embryonic-derived preadipocytes. On the one hand, loss of GCN5L2 leads to high incidence of apoptosis in the GCN5L2 mutants that begins before the onset of morphological abnormality.
Synonyms	Histone acetyltransferase KAT2A, Histone acetyltransferase GCN5, HsGCN5, HGCN5, Lysine acetyltransferase 2A, STAF97
Reference Data
Protein Families	Transcription Factors
Protein Pathways	Notch signaling pathway

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