CD62L (SELL) Mouse Monoclonal Antibody [Clone ID: DREG56]

CAT#: AM12066PU-N

CD62L (SELL) mouse monoclonal antibody, clone DREG56, Purified

Conjugation: Unconjugated FITC



Need it in bulk or conjugated?
Get a free quote

CNY 3,140.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name DREG56
Applications FC, FN, IHC, IP, WB
Recommend Dilution Flow Cytometry: 2 µg/ml.
Immunoprecipitation.
Western blot (Non-Reducing Conditions).
Immunohistochemistry on Frozen Sections.
Functional Application: Particularly effective in blocking of lymphocyte CD62L-mediated binding to peripheral lymph node HEV.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen PMA-activated human peripheral blood leukocytes
Specificity This antibody recognizes CD62L / L-selectin, a 65-76 kDa cell surface protein, expressed by neutrophils, monocytes, and subsets of T, B, and NK cells, that interacts with specific carbohydrates exposed on activated endothelial cells.
Formulation Phosphate buffered saline (PBS), pH~7.4 with 15 mM Sodium Azide as preservative
State: Purified
State: Liquid purified Ig fraction (> 95% by SDS-PAGE)
Concentration lot specific
Purification Protein A Affinity Chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
DO NOT FREEZE!
Gene Name selectin L
Background CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1). The level of CD62L expression can be used to help distinguish naive T cells from effector/memory T cells.
Synonyms SELL, LNHR, LYAM1, Leu-8, TQ1, gp90-MEL, LECAM1, LAM-1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...