Cd3e Hamster Monoclonal Antibody [Clone ID: 145-2C11]

CAT#: AM12132AC-N

Cd3e hamster monoclonal antibody, clone 145-2C11, APC

Conjugation: Unconjugated APC FITC PE



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CNY 3,280.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name 145-2C11
Applications FC
Recommend Dilution Flow cytometry: 2 μg/ml (starting point).
Reactivity Mouse
Host Hamster
Clonality Monoclonal
Immunogen Mouse BM10-37 cytotoxic T lymphocytes
Specificity This antibody reacts with mouse CD3 (epsilon subunit). It is commonly used as a phenotypic marker for mouse T cells.
Formulation Phosphate buffered saline (PBS) containing 15 mM sodium azide
Label: APC
State: Liquid Ig fraction
Label: Conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Concentration lot specific
Conjugation APC
Storage Condition Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name CD3 antigen, epsilon polypeptide
Background CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.
Synonyms T3/Leu-4
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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