Cd3e Hamster Monoclonal Antibody [Clone ID: 145-2C11]
CAT#: AM12132AC-N
Cd3e hamster monoclonal antibody, clone 145-2C11, APC
Conjugation: Unconjugated FITC PE
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CNY 3,280.00
Specifications
Product Data | |
Clone Name | 145-2C11 |
Applications | FC |
Recommend Dilution | Flow cytometry: 2 μg/ml (starting point). |
Reactivity | Mouse |
Host | Hamster |
Clonality | Monoclonal |
Immunogen | Mouse BM10-37 cytotoxic T lymphocytes |
Specificity | This antibody reacts with mouse CD3 (epsilon subunit). It is commonly used as a phenotypic marker for mouse T cells. |
Formulation | Phosphate buffered saline (PBS) containing 15 mM sodium azide Label: APC State: Liquid Ig fraction Label: Conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
Concentration | lot specific |
Conjugation | APC |
Storage Condition | Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Gene Name | CD3 antigen, epsilon polypeptide |
Database Link | |
Background | CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. |
Synonyms | T3/Leu-4 |
Reference Data |
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