BIN1 Mouse Monoclonal Antibody [Clone ID: BN-1]

Specifications

Product Data
Clone Name	BN-1
Applications	IHC, WB
Recommend Dilution	Western blot: Use at 0.25 μg/ml with the appropriate system to detect BIN1 in cells and tissues. Immunohistochemistry on Frozen Sections: Use at 0.5 μg/ml to detect BIN1 in Formalin/Acetone fixed tissues. Immunocytochemistry.
Reactivity	Chicken, Human, Mouse, Porcine, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant polypeptide containing amino acids 189-398 of Human Bin1.
Specificity	Recognizes BIN1. No cross reactivity with other proteins.
Formulation	1.2% Sodium Acetate containing 2mg BSA and 0.01 mg Sodium Azide as preservative. State: Purified State: Lyophilized purified IgG fraction
Reconstitution Method	Restore with 1.2% Sodium Acetate or neutral PBS.
Concentration	0.1 mg/ml (after reconstitution with 1 ml PBS).
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	bridging integrator 1
Database Link	Entrez Gene 274 Human UniProt ID O00499
Background	BIN1 (AMPH2) is a novel human gene product with features of a tumor suppressor protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a frequent aberration in human hepatocellular carcinomas . mutations in BIN1 cause centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic membranes, and that the functional interaction between BIN1 and DNM2 is necessary for normal muscle function and positioning of nuclei.
Synonyms	Bridging integrator 1, Amphiphysin-like protein, Amphiphysin II
Reference Data

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