GFAP Mouse Monoclonal Antibody [Clone ID: GA-8]
CAT#: AM20624PU-N
GFAP mouse monoclonal antibody, clone GA-8, Purified
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CNY 5,599.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | GA-8 |
Applications | IHC, WB |
Recommend Dilution | Western Blot: 0.5 - 1 μg/ml. Immunohistochemistry on frozen sections: 0.5 - 1 μg/ml. Immunohistochemistry on paraffin sections: 0.4 - 1 μg/ml. |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | GFAP from pig spinal cord. |
Specificity | This antibody reacts to GFAP. |
Formulation | 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative. State: Purified State: Lyphilized purified Ig fraction |
Reconstitution Method | Restore with 1.2% sodium acetate or neutral PBS |
Concentration | 0,1 mg/ml (after reconstitution with PBS) |
Purification | Affinity chromatography |
Conjugation | Unconjugated |
Storage Condition | Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | glial fibrillary acidic protein |
Database Link | |
Background | GGlial fibrillary acidic protein (GFAP) is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. GFAP has been located in rat kidney glomeruli and peritubular fibroblasts, leydig cells of testis, skin keratinocytes, osteocytes of bones, chondrocytes of epiglottis, bronchus, and stellate-shaped cells of the pancreas and liver. Its expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination. GFAP has also been shown to play a role in mitosis by adjusting the filament network present in the cell. During mitosis, there is an increase in the amount of phosphorylated GFAP, and a movement of this modified protein to the cleavage furrow. |
Synonyms | Glial Fibrillary Acidic Protein |
Reference Data | |
Protein Families | ES Cell Differentiation/IPS |
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