AKT1 Mouse Monoclonal Antibody [Clone ID: IML-26]

CAT#: AM20690PU-N

AKT1 mouse monoclonal antibody, clone IML-26, Purified



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CNY 5,599.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name IML-26
Applications WB
Recommend Dilution Western Blot: 0.25 - 0.5 μg/ml.
Reactivity Chicken, Human
Host Mouse
Clonality Monoclonal
Immunogen Synthetic peptide corresponding to amino acids 461-477 of human PKBalpha/Akt1.
Specificity This antibody reacts to AKT1 / PKB.
Formulation 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative
State: Purified
State: Lyphilized purified Ig fraction
Reconstitution Method Restore with 1.2% sodium acetate or neutral PBS
Concentration 0,1 mg/ml (after reconstitution with PBS)
Purification Affinity chromatography
Conjugation Unconjugated
Storage Condition Prior to reconstitution store at -20°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name AKT serine/threonine kinase 1
Background PKBalpha also knows as V-AKT murine thymoma vial oncogene homolog 1(ATK1). AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and is abrogated by mutations in the pleckstrin homology domain of AKT1. AKT1 gene is mapped to chromosome 14q32.3. Akt1/protein kinase B-alpha is critical for ischemic and VEGF-mediated angiogenesis. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo.
Synonyms Akt-1, RAC-PK-alpha, Protein kinase B, C-AKT
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase
Protein Pathways Acute myeloid leukemia, Adipocytokine signaling pathway, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Glioma, Insulin signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, Melanoma, mTOR signaling pathway, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Renal cell carcinoma, Small cell lung cancer, T cell receptor signaling pathway, Tight junction, Toll-like receptor signaling pathway, VEGF signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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