Frataxin (FXN) Mouse Monoclonal Antibody [Clone ID: 2FRA-1G2]

Specifications

Product Data
Clone Name	2FRA-1G2
Applications	IHC
Recommend Dilution	Immunohistochemistry on Frozen Sections: Not tested.  Immunohistochemistry on Paraffin Sections: 20 µg/ml (1/10). Proteinase K pretreatment for antigen retrieval recommended.  Suggested Positive Control: Swine brain cortex.
Reactivity	Human, Porcine
Host	Mouse
Clonality	Monoclonal
Immunogen	TrpE-Frataxin full length.
Specificity	This Monoclonal antibody Clone 2FRA-1G2 recognizes Human Frataxin. Frataxin is localized to the mitochondrion. Antigen Distribution: The antigen has been described in the heart, peripheral blood lymphocytes and dermal fibroblasts.
Formulation	Stock solution contains PBS, pH 7.2 with 5mg/ml BSA as stabilizer and 0.01% Kathon as a preservative State: Aff - Purified State: Lyophilized purified IgG fraction
Reconstitution Method	Restore by adding 0.5 ml distilled water
Concentration	0.5 mg/ml (after reconstitution)
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	frataxin
Database Link	Entrez Gene 2395 Human UniProt ID Q16595
Background	The function of frataxin is not entirely clear, but it seems to be involved in assembly of iron-sulfur clusters. It has been proposed to act as either an iron chaperone or an iron storage protein.
Synonyms	Frataxin mitochondrial, FRDA, Friedreich ataxia protein
Reference Data
Protein Families	Druggable Genome

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