CD62P (SELP) Mouse Monoclonal Antibody [Clone ID: AK4]

CAT#: AM26020RP-N

CD62P (SELP) mouse monoclonal antibody, clone AK4, PE

Conjugation: Unconjugated APC Biotin FITC PE



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CNY 4,340.00


货期*
5周

规格
    • 100 Tests

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Specifications

Product Data
Clone Name AK4
Applications FC
Recommend Dilution Flow Cytometry analysis of Human blood cells using 20 μl reagent / 100 μl of whole blood or 106 cells in a suspension.
The content of a vial (2 ml) is sufficient for 100 Tests.
Reactivity Human, Primate
Host Mouse
Clonality Monoclonal
Immunogen Human platelets
Specificity This antibody recognizes CD62P (P-selectin), a 140 kD single chain type I transmembrane glycoprotein present in secretory alpha-granules in platelets, in Weibel-Palade bodies in endothelial cells and in megakaryocytes; it is relocated to the plasma membrane upon activation.
Formulation Phosphate buffered saline (PBS)
Label: PE
State: Liquid purified Ig fraction
Stabilizer: 0.2% (w/v) high-grade protease free BSA
Preservative: 15 mM Sodium Azide
Label: Conjugated with R-Phycoerythrin under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use
Conjugation PE
Storage Condition Store the antibody at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Gene Name selectin P
Background CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.
Synonyms SELP, GMRP, GRMP, PADGEM, GMP-140, LECAM3
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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