HCV NS5B RdRp (1-19) Mouse Monoclonal Antibody [Clone ID: 8B2]

Specifications

Product Data
Clone Name	8B2
Applications	ELISA, FN, IP
Recommend Dilution	Reacts in ELISA, IP with genotype 1b (con-1) HCV NS5B protein. ELISA: 1:1000. Functional application: Blocks the RNAdependent RNA polymerase activity in vitro.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Hepatitis C Virus nonstructural protein 5B (NS5B) RNAdependent RNA polymerase (RdRp)
Specificity	This antibody detects Hepatitis C virus NS5B-protein (aa 1-9).
Formulation	PBS pH 7.4, with 0.09% sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store (in aliquots) at -20 to -70 °C. Avoid repeated freezing and thawing.
Background	Non-structural protein 5B (NS5B) represents the RNA-dependent RNA polymerase (RdRp) of Hepatitis C Virus, which is a small positive strand RNA virus in the family Flaviviridae. HCV is a major causative agent of acute and chronic hepatitis, hepatocellular carcinoma and liver cirrhosis. The single subunit RNA-dependent RNA polymerase is absolutely essential for the viral replication.
Synonyms	Hepatitis C Virus, RNA-directed RNA polymerase NS5B
Reference Data

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