Mx1 Mouse Monoclonal Antibody [Clone ID: AM39]
CAT#: AM26131PU-N
Mx1 mouse monoclonal antibody, clone AM39, Aff - Purified
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CNY 9,600.00
货期*
5周
规格
Cited in 2 publications. |
Specifications
Product Data | |
Clone Name | AM39 |
Applications | ELISA, WB |
Recommend Dilution | ELISA. Western blot. |
Reactivity | Bovine, Porcine |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Recombinant Porcine Mx1 protein |
Specificity | This Monoclonal antibody AM39 recognizes the Porcine Mx1 protein. |
Formulation | Stock solution contains PBS, pH 7.2 with 5 mg/ml BSA as a stabilizer and 0.09% Sodium Azide as a preservative State: Aff - Purified State: Lyophilized purified Ig fraction |
Reconstitution Method | Restore by adding 0.5 ml distilled water. |
Concentration | 0.4 mg/ml (after reconstitution) |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage Condition | Prior to reconstitution store at 2-8°C. |
Background | Mx proteins are cytoplasmic proteins induced by type-1 interferons (α and β) in leukocytes. However, there is a baseline level of expression even in the absence of viral infection. In humans, mainly monocytes and lymphocytes have been shown to express the Mx gene, whereas Mx expression is low in granulocytes. Mx proteins are high molecular weight GTPases of 70 - 80kD which belong to the dynamin superfamily. Mx proteins have a strong propensity to aggregate and form homooligomers. A unique property is their antiviral activity against many RNA viruses. |
Synonyms | Mx1 protein |
Reference Data |
Citations (2)
The use of this Antibodies has been cited in the following citations: |
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Synthetic RNAs Mimicking Structural Domains in the Foot-and-Mouth Disease Virus Genome Elicit a Broad Innate Immune Response in Porcine Cells Triggered by RIG-I and TLR Activation
,Borrego B, Rodrmguez-Pulido M, Revilla C, Alvarez B, Sobrino F, Dommnguez J, Saiz M,
Viruses
,PubMed ID 26193305
[MX1]
|
Influenza A infection of primary human airway epithelial cells up-regulates proteins related to purine metabolism and ubiquitin-related signaling.
,null,
Journal of proteome research
,PubMed ID 23750822
|
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