SLAMF1 Mouse Monoclonal Antibody [Clone ID: SLAM.4]

Specifications

Product Data
Clone Name	SLAM.4
Applications	FC, IF, IP
Recommend Dilution	Flow cytometry: Recommended dilution: 1-5 μg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human CD150-transfected 300.19 cells.
Specificity	This Monoclonal SLAM.4 antibody recognizes CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.
Formulation	Azide free phosphate buffered saline (PBS), pH~7.4, 0.2 μm filter sterilized State: Azide Free State: Liquid purified IgG fraction (> 95% pure by SDS-PAGE)
Concentration	lot specific
Purification	Aaffinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	signaling lymphocytic activation molecule family member 1
Database Link	Entrez Gene 6504 Human UniProt ID Q13291
Background	CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.
Synonyms	Slam, CDw150, Ipo-3
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

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