Timd4 Hamster Monoclonal Antibody [Clone ID: Kat5-18]
CAT#: AM26307PU-N
Timd4 hamster monoclonal antibody, clone Kat5-18, Purified
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CNY 4,077.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | Kat5-18 |
Applications | ELISA, FN, IF |
Recommend Dilution | Flow cytometry: The typical starting working dilution is 1:50. Functional assays: Blocks the engulfment of apoptotic cells by thymic macrophages. Immunoassays. Immunoflourescence. Does not work in Immunohoistochemistry on frozen and paraffin sections or Western blot. |
Reactivity | Mouse |
Host | Hamster |
Clonality | Monoclonal |
Immunogen | Mouse peritoneal cells |
Specificity | The monoclonal antibody Kat5-18 recognizes T-cell immunoglobulin and mucin domain containing molecule (TIMD-4, also called TIM-4). |
Formulation | PBS State: Purified State: Liquid purified 0.2 µm filtered purified Ig fraction Stabilizer: 0.1% bovine serum albumin |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store at 2 - 8 °C. |
Gene Name | T cell immunoglobulin and mucin domain containing 4 |
Database Link | |
Background | TIMD-4 is a type I transmembrane protein belonging to the immunoglobulin superfamily, containing one Ig-like V-type (immunoglobulin-like) domain. TIMD-4 is expressed in Mac1+ cells in spleen, lymph nodes and fetal liver. TIMD-4 binds apoptotic cells by recognizing phosphatidylserine via its immunoglobulin domain. TIMD-4 in fibroblasts enhanced their ability to engulf apoptotic cells. TIMD-4 is involved in regulating T-cell proliferation and lymphotoxin signaling. TIMD-4 and TIMD-1 are phosphatidylserine receptors for the engulfment of apoptotic cells, and are also involved in intracellular signaling in which exosomes are involved. |
Synonyms | TIMD-4, TIM4, TIM-4, T-cell membrane protein 4 |
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