C1QA Mouse Monoclonal Antibody [Clone ID: JL-1]
CAT#: AM26376FC-N
C1QA mouse monoclonal antibody, clone JL-1, FITC
Conjugation: Unconjugated Biotin
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CNY 8,738.00
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Specifications
Product Data | |
Clone Name | JL-1 |
Applications | ELISA, FN, IF, IHC, WB |
Recommend Dilution | Immunohistochemistry on frozen sections (1): Stains tissue sections which were fixed in acetone. As positive control a polyclonal anti-C1q antibody was used and as negative control an isotype matched monoclonal antibody (Ref.1). The typical starting working dilution is 1:50. Functional assays (1): Antibody JL-1 was administered to mice resulting in depletion of circulating C1q, glomerular deposition of C1q and induction of anti-C1q autoantibodies in susceptible mice. As a negative control an isotype matched monoclonal antibody was used (Ref.1). Immunoassays (1,2). Immunoflourescence (1). Western blot (3): The typical starting working dilution is 1:50. Positive control: Spleen and kidney tissue of wild-type mice (Ref.1). Negative control: Spleen and kidney tissue of C1q -/- mice (Ref.1). |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified mouse C1q |
Specificity | The monoclonal antibody JL-1 recognizes the collagen-like region (CLR) of mouse C1q. |
Formulation | PBS Label: FITC State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 1% bovine serum albumin Preservative: 0.02% sodium azide |
Concentration | lot specific |
Conjugation | FITC |
Storage Condition | Store at 2 - 8 °C. |
Gene Name | complement component 1, q subcomponent, A chain |
Database Link | |
Background | C1q is a 459 kDa molecule consisting of three individual polypeptide chains. The antibody has been generated by immunization of C1q-/- C57BL/6 mice with purified mouse C1q. |
Synonyms | Complement C1q, Complement 1q |
Reference Data |
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