TNF alpha (TNF) Mouse Monoclonal Antibody [Clone ID: Mab11]

Specifications

Product Data
Clone Name	Mab11
Applications	FC
Recommend Dilution	Flow Cytometry analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Reactivity	Human, Porcine, Primate
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human TNF-alpha
Specificity	This antibody recognizes human 17-26 kDa cytokine TNF-alpha (tumor necrosis factor alpha).
Formulation	Phosphate buffered saline (PBS) Label: FITC State: Liquid purified Ig fraction Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) Preservative: 15 mM sodium azide Label: Conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use.
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	tumor necrosis factor
Database Link	Entrez Gene 7124 Human UniProt ID P01375
Background	TNF-alpha is a cytokine produced by monocytes, macrophages, neutrophils, NK cells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha easily forms stable trimers, but also other multimeric complexes. In the immune system, it is an important regulator, which has cytolytic and cytostatic activity against a range of tumor cells, increases fibroblast proliferation and supports neutrophil chemotaxis and phagocytosis.
Synonyms	TNF, TNF-a, TNFA, TNFSF2, Cachectin
Reference Data

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