FPR3 Mouse Monoclonal Antibody [Clone ID: 2G3]

Specifications

Product Data
Clone Name	2G3
Applications	FC
Recommend Dilution	FACS. IHC (weak reaction).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	DNA vaccine
Specificity	This antibody detects human FPRL2.
Formulation	Phosphate buffered saline pH 7.2 (PBS) State: Purified State: Lyophilized affinity purified Ig fraction Stabilizer: 5 mg/ml bovine serum albumin (BSA) Preservative: 0.1 % Kathon
Reconstitution Method	Reconstitute by adding 0.5 ml distilled water.
Purification	Protein G purified
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	formyl peptide receptor 3
Database Link	Entrez Gene 2359 Human UniProt ID P25089
Background	FPRL2 is a 353 amino acid G - protein coupled receptor. Its particular distribution on macrophage subsets of the lung, intestine and skin suggest an involvement in innate immunity against helminths or in allergic diseases. Fittingly, the recept or has also been identified on eosinophils, but not on neutrophils. The endogenous peptide F2L, an acetylated 21 amino acid peptide derived from heme - binding protein, is a most specific ligand for FPRL2 and causes chemotaxis but not degranulation in human eosinophils. F2L is also chemotactic for plasmacytoid dendritic cells which express FPRL2 and up - regulate this receptor during maturation.
Synonyms	FML2_HUMAN; FMLP-R-II; FMLPY; FPRH1; FPRH2; FPRL2; RMLP-R-I
Reference Data

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