CBX1 Mouse Monoclonal Antibody [Clone ID: 1MOD-1A9]

CAT#: AM26739PU-N

CBX1 mouse monoclonal antibody, clone 1MOD-1A9, Purified



Need it in bulk or conjugated?
Get a free quote

CNY 8,981.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name 1MOD-1A9
Applications IHC
Recommend Dilution Immunohistochemistry on paraffin sections: 4 µg/ml (1:50). Microwave pretreatment in citrate buffer is recommended for antigen retrieval.
Suggested Positive control: Human / Swine brain cortex.
Reactivity Human, Mouse, Porcine
Host Mouse
Clonality Monoclonal
Immunogen Recombinant mouse HP1β
Specificity This antibody detects HP1β.
Formulation Phosphate buffered saline pH 7.2 (PBS)
State: Purified
State: Lyophilized affinity purified Ig fraction
Stabilizer: 5 mg/ml bovine serum albumin (BSA)
Preservative: 0.01% Kathon
Reconstitution Method Reconstitute by adding 0.5 ml distilled water. This stock solution contains 0.2 mg/ml IgG.
Conjugation Unconjugated
Storage Condition Store lyophilized at 2-8°C for 6 month or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Gene Name chromobox 1
Background Heterochromatin Protein 1 (HP1) ("Chromobox Homolog", CBX) includes three isoforms in mammals, designated α, β, and γ. HP1 proteins are approximately 25 kDa in size. They are highly conserved adapter proteins with important regulatory functions in the cell nucleus. These functions include notably gene silencing by heterochromatin formation. HP1 proteins are fundamental units of heterochromatin packaging that are enriched at the centromeres and telomeres of nearly all Eukaryotic chromosomes. HP1 β and γ also localize to euchromatic sites in the genome. Members of the HP1 family are characterized by an N-terminal chromodomain and a C- terminal chromoshadow domain, separated by a Hinge region. Chromodomain and chromoshadow domain establish secondary interactions with a large number of other proteins. HP1 proteins are subject to multiple types of post - translational modifications, including phosphorylation, acetylation, methylation, ubiquitination and sumoylation, suggesting multiple means of regulation.
Synonyms Chromobox protein homolog 1, M31, Heterochromatin protein p25, HP1Hsbeta, p25beta, HP1-beta, HP1 beta
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...