CD300E Mouse Monoclonal Antibody [Clone ID: UP-H2]

Specifications

Product Data
Clone Name	UP-H2
Applications	FC
Recommend Dilution	Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	CD300e-HA-transfected cells
Specificity	This antibody recognizes CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
Formulation	Phosphate buffered saline (PBS) Label: APC State: Liquid purified Ig fraction Stabilizer: 0.2% (w/v) high-grade protease free BSA Preservative: 15 mM Sodium Azide Label: Conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Conjugation	APC
Storage Condition	Store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	CD300e molecule
Database Link	Entrez Gene 342510 Human UniProt ID Q496F6
Background	CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.
Synonyms	CLM-2, CD300LE, CLM2, IREM2, CMRF35-A5
Reference Data

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