CD300E Mouse Monoclonal Antibody [Clone ID: UP-H2]

Specifications

Product Data
Clone Name	UP-H2
Applications	FC, FN, IP, WB
Recommend Dilution	Flow cytometry. Immunoprecipitation. Western blot. Functional application: stimulation.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	CD300e-HA-transfected cells
Specificity	This antibody recognizes CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
Formulation	Phosphate buffered saline (PBS) State: Purified State: Liquid Ig fraction Preservative: 15 mM sodium azide, approx. pH 7.4
Concentration	lot specific
Purification	Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	CD300e molecule
Database Link	Entrez Gene 342510 Human UniProt ID Q496F6
Background	CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.
Synonyms	CLM-2, CD300LE, CLM2, IREM2, CMRF35-A5
Reference Data

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