Factor VII (F7) (+VIIa) Mouse Monoclonal Antibody [Clone ID: AD-1]

Specifications

Product Data
Clone Name	AD-1
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human Factor VII (AD-1) purified from plasma.
Specificity	This antibody is specific for factor VII/VIIa (AD-1).
Formulation	PBS containing 0.02% sodium azide (NaN3) as preservative State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	coagulation factor VII
Database Link	Entrez Gene 2155 Human UniProt ID P08709
Background	Human blood coagulation factor VII is a 50 kD, vitamin K dependent, plasma glycoprotein synthesized in the liver and secreted into the blood as a single chain zymogen of serine protease factor VIIa. Factor VII participates in a cascade of reactions leading to the coagulation of blood and contains two Epidermal Growth Factor (EGF) domains. This antibody recognizes an epitope in the factor VIIa heavy chain. Factor VII participates in the extrinsic pathway of blood coagulation in an Activated form called factor VIIa. Factor VII can be converted to VIIa by Factor IXa or thrombin.
Synonyms	Proconvertin, SPCA
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Complement and coagulation cascades

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