Cd27 Hamster Monoclonal Antibody [Clone ID: LG.3A10]
CAT#: AM31861FC-N
Cd27 hamster monoclonal antibody, clone LG.3A10, FITC
Conjugation: Unconjugated Biotin PE
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CNY 3,600.00
Specifications
Product Data | |
Clone Name | LG.3A10 |
Applications | FC, FN, IHC |
Recommend Dilution | Flow Cytometry. Functional Studies (stimulating). Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections. |
Reactivity | Mouse |
Host | Hamster |
Clonality | Monoclonal |
Immunogen | MCD27 tag expressing clones AR0524 and AR0530 from Armenian Hamster spleen. |
Specificity | Recognizes Mouse CD27 receptor. |
Formulation | PBS Label: FITC State: Liquid purified IgG fraction Stabilizer: EIA grade BSA to bring total protein concentration to 4-5 mg/ml Preservative: 0.02% Sodium Azide |
Concentration | lot specific |
Purification | Protein G Chromatography |
Conjugation | FITC |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
Gene Name | CD27 antigen |
Database Link | |
Background | CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both αβ and γδ T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8- precursors. There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events. |
Synonyms | TNFRSF7, CD27L receptor, T14 |
Note | Tests Results: Tissue Distribution by Flow Cytometry Analysis: Mouse Strain: BALB/c Cell Concentration : 1x10e6 cells per tests Antibody Concentration Used: 0.5 µg/10e6 cells Isotypic Control: PE Hamster IgG |
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