alpha 1 Spectrin (SPTA1) Mouse Monoclonal Antibody [Clone ID: AF10]

Specifications

Product Data
Clone Name	AF10
Applications	IF, IHC, IP, WB
Recommend Dilution	Western blotting: at least 1/1000 dilution. Immunoprecipitation. Immunocytochemistry on Frozen Sections.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Ghost proteins of Human red blood cells. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
Specificity	The antibody clone AF10 is specific to the 240kD Erythroid alpha-Spectrin.  This antibody is suitable for Various immunochemical reactions to detect Erythroid Spectrins, Identification of Erythroid leukemias (Ref.1).
Formulation	PBS State: Purified State: Liquid purified Ig fraction Stabilizer: 1.0% BSA Preservative: 0.09% Sodium Azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	spectrin alpha, erythrocytic 1
Database Link	Entrez Gene 6708 Human UniProt ID P02549
Background	Erythroid spectrins, some other proteins of erythroid cytoskeleton, and the transmembrane protein band 3 are highly specific for erythrocytes and their progenitors. They are more reliable markers for erythroid differentiation than Glycophorin A, the commonly used marker for erythroid differentiation, because Glycophorin A is expressed also in many cell lines otherwise exhibiting mainly megakaryotic charasteristics.
Synonyms	SPTA, Erythroid alpha-spectrin
Reference Data

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