CD11a (ITGAL) Mouse Monoclonal Antibody [Clone ID: 87-6F9]

CAT#: AM32398PU-N

CD11a (ITGAL) mouse monoclonal antibody, clone 87-6F9, Purified



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CNY 4,724.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name 87-6F9
Applications IHC
Recommend Dilution Flow Cytometry.
Immunohistochemistry on frozen section.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen A BALB/c mouse was immunized and SP2/0 cells were used for fusion with splenocytes.
Specificity This antibody reacts to CD11a.
Formulation PBS
State: Purified
State: Liquid purified Ig fraction
Preservative: 0.05% sodium azide
Concentration lot specific
Conjugation Unconjugated
Storage Condition

Store the antibody undiluted at 2-8°C.

Gene Name integrin subunit alpha L
Background

CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages with increase in levels on memory T cells. CD11a or LFA-1 has a key role in mediating leukocyte adhesion to endothelium during inflammatory responses through binding to ICAM-1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many T cell functions and immune phenomena. Mol. weight in SDS gels is about 180 kD. Part of heterodimer with CD18 (integrin beta-2). A defect in beta-2 expression results in leucocytes adhesion deficiency (LAD) in which patients suffer from recurring bacterial infections.

Synonyms Integrin alpha-L, LFA1, LFA-1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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