HINT2 Mouse Monoclonal Antibody [Clone ID: AT5B10]
CAT#: AM50638PU-N
HINT2 mouse monoclonal antibody, clone AT5B10, Purified
Size: 50 ul
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CNY 6,620.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | AT5B10 |
Applications | ELISA, FC, WB |
Recommend Dilution | The antibody has been tested by ELISA, Western blot analysis and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Recombinant human HINT2 (18-163aa) purified from E. coli. |
Formulation | Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol. State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein-A affinity chromatography |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | histidine triad nucleotide binding protein 2 |
Database Link | |
Background | Histidine triad nucleotide binding protein 2 (HINT2) is a mitochondrial protein. This protein is an AMP-lysine hydrolase and phosphoamidase and may contribute to tumor suppression. This protein is a member of the HIT superfamily and Hint subfamily, which are characterized as nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides. HINT2 regulates steroidogenesis through calcium-dependent and calcium-independent siglling pathways that may serve to maintain a favorable mitochondrial potential. Its role in calcium homeostasis may also contribute to its proapoptotic function in hepatocytes and other non-steroidogenic cells, though the exact mechanism remains unclear. |
Synonyms | HINT-2, HINT-3, HIT-17kDa, PKCI-1-related HIT protein |
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