IGF2 Rabbit Polyclonal Antibody
CAT#: AP02105SU-N
IGF2 rabbit polyclonal antibody, Serum
Size: 20 ul
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CNY 5,423.00
货期*
5周
规格
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | Western blot: 1/1000-1/2000. |
Reactivity | Bovine, Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Human Insulin-like Growth Factor-2 (Somatomedin A) |
Specificity | This antibody recognizes IGF-2. |
Formulation | State: Serum State: Liquid serum Preservative: 0.09% Sodium Azide |
Reconstitution Method | Restore in aqua bidest to initial volume. |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | insulin like growth factor 2 |
Database Link | |
Background | Insulin-like growth factor II (also known as multiplication stimulating activity or MSA) and insulin-like growth factor I (IGF-I) belong to the family of insulin-like growth factors which are structurally homologous to proinsulin. Mature IGF-I and IGF-II are highly conserved and share approx imately 70% amino acid sequence identity. Mouse IGF-II, a 67 amino acid protein, has a predicted molecular mass of approximately 7.4 kDa. Mouse and human IGF-II share 91% sequence identity. Insulin-like growth factor II has autocrine, paracrine, and endocrine functions. It is a potent mitogenic growth factor that mediates growth-promoting activities in embryonic development. IGF-II binds the IGF-II receptor with high affinity. IGF-I and IGF II are expressed in many tissues and cell types. IGF-II is mitogenic for a variety of cultured cells including human or chicken fibroblasts, mouse 3T3 cells, normal rat kidney cells, and MCF-7 human breast carcinoma cells. |
Synonyms | IGF-II, Somatomedin-A |
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