PAI1 (SERPINE1) Goat Polyclonal Antibody

CAT#: AP02162PU-S

PAI1 (SERPINE1) goat polyclonal antibody, Purified

Size: 10 ug 100 ug



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CNY 1,990.00


货期*
5周

规格
    • 10 ug

Product images

Specifications

Product Data
Applications ELISA, IHC, R
Recommend Dilution ELISA.
RIA.
Immunohistochemistry on Frozen Sections: 1/50-1/100.
Immunohistochemistry on Paraffin Sections: 1/50 (Pretreatment with 0.05% Pronase E for 20 minutes recommended).
Reactivity Human
Host Goat
Clonality Polyclonal
Immunogen Purified human PAI-1
Specificity This antibody detects PAI 1.
There were no cross reactivities obtained with human tPA ; uPA; and PAI-2.
Formulation 50mM TRIS, pH 7.4 containing 0.04% Thimerosal as preservative.
State: Purified
State: Lyophilized purified IgG fraction.
Reconstitution Method Restore in aqua bidest to 1 mg/ml.
Purification Protein G Chromatography.
Conjugation Unconjugated
Storage Condition Store lyophilized at 2-8°C and reconstituted at -20°C.
Avoid repeated freezing and thawing.
Gene Name serpin family E member 1
Background PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type plasminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder.
Synonyms Serpin E1, PLANH1, Plasminogen Activator Inhibitor 1, PAI-1, PAI
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades, p53 signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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