ATF 4 (ATF4) pSer245 Rabbit Polyclonal Antibody
CAT#: AP02352PU-N
ATF 4 (ATF4) pSer245 rabbit polyclonal antibody, Aff - Purified
Size: 50 ul
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CNY 2,250.00
货期*
2周
规格
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | Suitable for use in Immunohistochemistry (1:50~1:100). |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The antiserum was produced against synthesized phosphopeptide derived from human ATF4 around the phosphorylation site of serine 245 (N-R-Sp-L-P). |
Specificity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. ATF4 (phospho-Ser245) antibody detects endogenous levels of ATF4 only when phosphorylated at serine 245. |
Formulation | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% glycerol. State: Aff - Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Immunoaffinity chromatography. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Gene Name | activating transcription factor 4 |
Database Link | |
Background | ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. |
Synonyms | CREB2, CREB-2, TXREB, Activating transcription factor 4, ATF-4 |
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