NMDAR1 (GRIN1) pSer896 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Suitable for use in Western blot (1:500~1:1000).
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against synthesized phosphopeptide derived from human NMDAR1 around the phosphorylation site of serine 896 (R-R-SP-S-K).
Specificity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. NMDAR1 (phospho-Ser896) antibody detects endogenous levels of NMDAR1 only when phosphorylated at serine 896.
Formulation	PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol. State: Aff - Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Immunoaffinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	glutamate ionotropic receptor NMDA type subunit 1
Database Link	Entrez Gene 2902 Human UniProt ID Q05586
Background	NMDA receptor subtypes of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. NMDAR1 plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission and is involved in the cell surface targeting of NMDA receptors.
Synonyms	NMDAR1,GRIN1
Reference Data

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