Ionotropic Glutamate receptor 2 (GRIA2) pSer880 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blot: 1:500~1:1000.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against synthesized phosphopeptide derived from human Glutamate receptor 2 (Precursor) around the phosphorylation site of serine 880 (I-E-SP-V-K).
Specificity	Glutamate receptor 2 (Precursor) antibody detects endogenous levels of Glutamate receptor 2 (Precursor) only when phosphorylated at serine 880.
Formulation	PBS(without Mg2+ and Ca2+), pH 7.4 containing 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid purified IgG
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	glutamate ionotropic receptor AMPA type subunit 2
Database Link	Entrez Gene 2891 Human UniProt ID P42262
Background	Glutamate receptors sensitive to AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropionate) are ligand-activated cation channels that mediate the fast component of excitatory postsynaptic currents in neurons of the central nervous system. These channels are assembled from 4 related subunits, GLURA (GRIA1), GLURB (GRIA2), GLURC (GRIA3), GLURD (GRIA4), with the GLURB subunit rendering the channel almost impermeable to Ca(2+).
Synonyms	GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA2, GRIA2
Reference Data

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