JUNB Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Immunohistochemistry on paraffin sections: 1/50~1/100. Immunofluorescence: 1/100~1/200.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide sequuence aroundd aa 77~81 (GG-A-S-L-K) derived from Human JunB.
Specificity	JunB antibody detects endogenous levels of total JunB protein.
Formulation	PBS (without Mg2+ and Ca2+), pH 7.4 containing 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol State: Aff - Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Affinity-Chromatography using epitope-specific immunogen
Conjugation	Unconjugated
Storage Condition	Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	JunB proto-oncogene, AP-1 transcription factor subunit
Database Link	Entrez Gene 3726 Human UniProt ID P17275
Background	The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.
Synonyms	JUNB
Note	Molecular Weight: 43 kDa
Reference Data

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