MAPK8 + MAPK9 + MAPK10 Sheep Polyclonal Antibody

Specifications

Product Data
Applications	IP
Recommend Dilution	Immunoprecipitation: 1 - 10 µg/ml, of the catalyticaly active form of SAP kinase, in vitro kinase assay.
Reactivity	Human, Mouse, Rat
Host	Sheep
Clonality	Polyclonal
Specificity	This antibody reacts to Stress Associated Protein Kinase (SAP kinase).
Formulation	State: Purified
Concentration	lot specific
Purification	Purified
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	SAP kinase detects native SAP kinase by immunoprecipitation in rat and human (HeLa) cells. SAP kinase is induced by stress agonists such as UV irradiation, heat shock and inflammatory cytokines. These stress stimuli result in the phosphorylation of and enzymatic activation of Stress Activated Protein Kinases (SAP kinases). Three SAP kinase gene are known to exist, a, b and g , which are differentially spliced giving 10 gene products in total.
Synonyms	MAPK8/9/10, SAPK alpha beta gamma, JNK1, 2, 3
Reference Data

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