SAMD8 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot: 5-10 µg/ml.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Full-length recombinant sphingomyelin synthase r fusion protein.
Specificity	This antibody reacts to Sphingomyelin synthase-related protein 1.
Formulation	Phosphate buffered saline with 0.08% Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing.
Gene Name	sterile alpha motif domain containing 8
Database Link	Entrez Gene 142891 Human UniProt ID Q96LT4
Background	Sphingomyelin (SM) is a major component of animal plasma membranes. Its production involves the transfer of phosphocholine from phosphatidylcholine and then onto ceramide. This also yields diacylglycerol as a side product. The reaction is catalysed by SM synthase, an important enzyme in the regulation of diacylglycerol and ceramide as anti- and proapoptotic stimuli. SM synthesis occurs in the lumen of the Golgi as well as on or at the cell surface. It is uncertain which SM enzyme forms are present at these differnet cellular locations. Human, mouse and Caenorhabditis elegans genomes each contain at least two different SM synthase (SMS) genes. Human SMS1 is localised to the Golgi, SMS2 resides primarily at the plasma membrane.
Synonyms	FLJ25082; SMSr
Reference Data
Protein Families	Transmembrane

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