OGR1 (GPR68) (1st Extracel. Dom.) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA. Immunohistochemistry on Paraffin Sections: 10 - 20 µg/ml.
Reactivity	Human, Monkey, Rat, Mouse, Gorilla
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic 18 amino acid peptide from 1st extracellular domain of human GPR68
Specificity	This antibody detects G Protein-Coupled Receptor OGR1/GPR68, 1st extracellular domain.
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer. Avoid repeated freezing and thawing.
Gene Name	G protein-coupled receptor 68
Database Link	Entrez Gene 8111 Human UniProt ID Q15743
Background	OGR1, a Lysophospholipid/Lysosphingolipid Receptor, was isolated by degenerate PCR from an ovarian cell line cDNA library. It is not expressed in normal ovary. OGR1 binds sphingosylphosporylcholine, a lipid molecule involved in cell growth and survival. Recently, OGR1 has been shown to act as a proton-sensing receptor stimulating inositol phosphate formation (Ludwig et al. 2003).
Synonyms	Sphingosylphosphorylcholine receptor, G-protein coupled receptor 68, GPR12A
Reference Data

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