ZMYM2 (1250-1300) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 10 µg/ml. Western Blot: 0.1 - 1 µg/ml.
Reactivity	Bovine, Canine, Chicken, Human, Monkey, Mouse, Rat, Orang-Utan
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to the amino acids 1250-1300 of human Zinc finger protein 198
Specificity	This antibody recognizes Zinc Finger Protein 198 (ZNF198) (ZMYM2) at aa 1250-1300.
Formulation	PBS containing 0.05% Sodium Azide as preservative and 0.2% Gelatin as stabilizer State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	zinc finger MYM-type containing 2
Database Link	Entrez Gene 7750 Human UniProt ID Q9UBW7
Background	Zfp198 (zinc finger protein 198, also known as ZNF198 or Zinc finger MYM-type protein 2) is a transcription factor that contains 9 MYM-type zinc fingers. Zfp198 interacts with, and is modified by, SUMO1 and colocalises with PML to nuclear bodies. Zfp198 has also been shown to stabilise the LSD1-CoREST-HDAC1 complex on chromatin through its MYM-type zinc fingers. A chromosomal translocation resulting in a Zfp198-FGFR1 fusion is associated with stem cell leukemia lymphoma syndrome (SCLL). SCLL usually presents as a lymphoblastic lymphoma in association with a myeloproliferative disorder.
Synonyms	ZNF198, FIM, RAMP
Reference Data

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