ENPP1 (915-925) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 2.5 - 5 µg/ml.
Reactivity	Human, Mouse, Rat, Rabbit
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from C-terminus of Human ENPP1, aa 915-925 (NP_006199.2)
Specificity	Specific to Human ENPP1 (C-term).
Formulation	Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ectonucleotide pyrophosphatase/phosphodiesterase 1
Database Link	Entrez Gene 5167 Human UniProt ID P22413
Background	ENPP1 has a broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. It can hydrolyze nucleoside 5' triphosphates such as ATP, GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate. It can also hydrolyze diadenosine polyphosphates and 3',5'-cAMP to AMP. It may play a role in the regulation of pyrophosphate production, the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling.
Synonyms	ENPP-1, M6S1, NPPS, PC1, PDNP1, E-NPP 1
Reference Data

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