Pebp1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1/1000.
Reactivity	Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Native PEBP protein purified from rat.
Specificity	This antibody recognizes the ~22k PEBP protein in Western blots.
Formulation	State: Serum State: Neat Serum.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	phosphatidylethanolamine binding protein 1
Database Link	Entrez Gene 29542 Rat UniProt ID P31044
Background	Phosphatidylethanolamine binding protein (PEBP), also known as Raf kinase inhibitory protein (RKIP) is a highly conserved multifunctional protein that modulates the Raf/MAPK signaling cascade and has been implicated as a suppressor of metastatic cancer (Trakul N et al., 2005). PEBP has been shown to not only inhibit cell proliferation but also to induce differentiation of human keratinocytes (Yamazaki et al., 2004). Dysregulation of calpain activity results in cellular degeneration in conditions such as Alzheimer’s disease and recently PEBP has been identified as a potential in vivo calpain substrate (Chen at al., 2006)
Synonyms	PEBP-1, PEBP, Prostatic-binding protein, PBP, Raf kinase inhibitor protein, HCNPpp
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.