VIP Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Frozen and Paraffin Sections. Working Dilution: 1/2500-1/5000 using PAP, or 1/1500-1/3000 using FITC with overnight incubation at 2-8°C. Recommended Positive Control: Formalin-fixed paraffin sections of cat ileum.
Reactivity	Feline, Fish, Human, Mammalian, Porcine, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Purified porcine VIP.
Specificity	Antibody AM09102SU-N recognizes VIP (Vasoactive intestinal peptide). Absorption with 10-100 µg immunogen per ml diluted antiserum abolishes the staining, while PHI PHI, secretin, glucagon, GIP, and CCK do not.
Formulation	State: Serum State: Lyophilized Undiluted Serum.
Reconstitution Method	Dissolve the antiserum in 50-100 µl distilled water, and dilute further in 0.1 M PBS with 1% BSA and 0.09% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	vasoactive intestinal peptide
Database Link	Entrez Gene 117064 RatEntrez Gene 7432 Human UniProt ID P01282
Background	VIP is localized in nerve fibers of the central and peripheral nervous system, and is probably acting as a neurotransmitter. Smooth muscle relaxation, vasodilation and secretion from exocrine glands are some of the effects of VIP. The Verner-Morrison or Watery Diarrhea Hypokaliemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors. These VIP producing tumors are usually neuroblastomas of endocrine tumors in the pancreas.
Synonyms	VIP, Vasoactive intestinal peptide
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane

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