Helicobacter pylori Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/100-1/200 Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended. Use Polymer anti Mouse/Rabbit IgG as a detection system. Positive Control: Helicobacter pylori infected tissue.
Reactivity	Helicobacter pylori
Host	Rabbit
Clonality	Polyclonal
Immunogen	Total lyaste of Helicobacter pylori.
Specificity	This antibody recognises Helicobacter pylori.
Formulation	State: Purified State: Liquid purified Total IgG fraction with 0.2% BSA and 15mM Sodium Azide.
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Background	The spiral shaped bacterium Helicobacter Pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. Helicobacter Pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcimona and low grade lymphoma of mucosa associated lymphoid tissue in the stomach. More recently this bacterium has also been implicated with a number of vascular disorders including heart disease. It is not clear how H. pylori is transmitted or why some patients become symptomatic while others do not. The bacteria are most likely spread from person to person through fecal to oral or oral to oral routes. Possible environmental reservoirs include contaminated water sources. Serological tests that measure specific H. pylori IgG antibodies can determine if a person has been infected although these methods do have drawbacks and limitations.
Synonyms	H. pylori
Reference Data

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