MAPKAP Kinase 2 (MAPKAPK2) pSer272 Rabbit Polyclonal Antibody
CAT#: AP12635PU-N
MAPKAP Kinase 2 (MAPKAPK2) pSer272 rabbit polyclonal antibody, Aff - Purified
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CNY 6,446.00
货期*
5周
规格
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | ELISA: 1/1,000. Dot Blot: 1/500. Immunohistochemistry: 1/50-1/100. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S272 of human MAPKAPK2. |
Specificity | This antibody detects MAPKAP Kinase-2 (MAPKAPK2) pSer272. Predicted to cross react with Mouse and Rabbit (100% Antigen Homology). |
Formulation | PBS with 0.09% (W/V) Sodium Azide as preservative. State: Aff - Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | mitogen-activated protein kinase-activated protein kinase 2 |
Database Link | |
Background | This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. |
Synonyms | MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MK2, MAPKAPK2 |
Note | Calculated Molecular weight: 45568 Da |
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