AMPK alpha 1 (PRKAA1) (C-term) Rabbit Polyclonal Antibody
CAT#: AP13877PU-N
AMPK alpha 1 (PRKAA1) (C-term) rabbit polyclonal antibody, Purified
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CNY 6,314.00
货期*
5周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | ELISA 1:1,000. Western blot 1:100 - 1:500. |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human AMPK alpha 1. |
Specificity | This antibody detects AMPK alpha 1 at C-term. |
Formulation | PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Gene Name | protein kinase AMP-activated catalytic subunit alpha 1 |
Database Link | |
Background | AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK. |
Synonyms | AMPK1, AMPK alpha-1 chain |
Note | Molecular weight: 62793 Da. |
Reference Data |
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