PCK1 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1/1,000. Western blotting: 1/1,000. Immunohistochemistry: 1/50-1/100.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 40-70 amino acids from the N-terminal region of Human PCK1.
Specificity	This antibody recognizes PCK1.
Formulation	PBS with 0.09% (W/V) Sodium Azide State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	phosphoenolpyruvate carboxykinase 1
Database Link	Entrez Gene 5105 Human UniProt ID P35558
Background	This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. A mitochondrial isozyme of the encoded protein also has been characterized.
Synonyms	PEPCK-C, PEPCKC, Phosphoenolpyruvate carboxylase, PEP carboxykinase
Reference Data

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