PSME2 (Center) Rabbit Polyclonal Antibody

CAT#: AP17685PU-N

PSME2 (Center) rabbit polyclonal antibody



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CNY 6,160.00


货期*
5周

规格
    • 400 ul

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Specifications

Product Data
Applications WB
Recommend Dilution ELISA: 1/1,000.
Western blotting: 1/100 - 1/500.
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide selected from the Center region of human PSME2
Specificity This antibody reacts to PSME2.
Formulation PBS with 0.09% (W/V) sodium azide
State: Liquid purified Ig
Concentration lot specific
Purification Affinity chromatography on Protein A
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name proteasome activator subunit 2
Background The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. PSME2 is the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon.
Synonyms Proteasome activator, PA28b, PA28beta
Reference Data
Protein Pathways Antigen processing and presentation, Proteasome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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