Tyrosinase (TYR) (C-term) Rabbit Polyclonal Antibody
CAT#: AP17815PU-N
Tyrosinase (TYR) (C-term) rabbit polyclonal antibody, Purified
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CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | FC, IF, IHC, WB |
Recommend Dilution | ELISA: 1/1000. Western Blot: 1/1000. Immunofluorescence: 1/10-1/50. Flow Cytometry: 1/10-1/50. Immunohistochemistry on Paraffin Sections: 1/10-1/50. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 486-513 amino acids from the C-terminal region of Human Tyrosinase. |
Specificity | This antibody recognizes Human Tyrosinase (TYR). Other species not tested. |
Formulation | PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide |
Concentration | lot specific |
Purification | Saturated Ammonium Sulfate (SAS) precipitation |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Predicted Protein Size | 60393 Da |
Gene Name | tyrosinase |
Database Link | |
Background | TYR catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The protein has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this protein result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. |
Synonyms | LB24-AB; OCA1A; OCAIA; SHEP3; SK29-AB; tyrosinase |
Reference Data | |
Protein Families | Transmembrane |
Protein Pathways | Melanogenesis, Metabolic pathways, Riboflavin metabolism, Tyrosine metabolism |
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