ZWINT (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	ELISA: 1/1000. Western blotting: 1/1000. Flow Cytometry: 1/10-1/50. Immunohistochemistry: 1/50-1/100.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 59-88 selected from the Center region of Human ZWINT
Specificity	This antibody recognizes ZW10 interactor/ZWINT (Center).
Formulation	PBS State: Purified State: Liquid purified Ig fraction. Preservative: 0.09% (W/V) Sodium Azide
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ZW10 interacting kinetochore protein
Database Link	Entrez Gene 11130 Human UniProt ID O95229
Background	ZWINT is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells.
Synonyms	Zwint-1
Note	Calculated MW: 31293 Da
Reference Data
Protein Families	Druggable Genome

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