ALD2 (pan ALDH) Rabbit Polyclonal Antibody

CAT#: AP20104AF-N

ALD2 (pan ALDH) rabbit polyclonal antibody, Azide Free



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CNY 3,402.00


货期*
5周

规格
    • 10 mg

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Specifications

Product Data
Applications ELISA, ID, IF, IP, R, WB
Recommend Dilution This product is intended for use in precipitating and non-precipitating antibody-binding assays such as e.g., ELISA and Western blotting and Immunofluorescence or Histochemical techniques (1/1,000-1/6,000).
Reactivity Bakers Yeast
Host Rabbit
Clonality Polyclonal
Immunogen Aldehyde dehydrogenase isolated and purified from Baker's Yeast.
Freund's complete adjuvant is used in the first step of the immunization procedure.
Specificity The reagents were evaluated for potency, purity and specificity using most or all of the following techniques: Immunoelectrophoresis, Cross-Immunoelectrophoresis, single Radial Immunodiffusion (Ouchterlony), block titration, ELISA, Immunoblotting and Enzyme Inhibition.
Cross-reactivities against enzymes of other sources may occur but have not been determined.
Recognizes Aldehyde Dehydrogenase.
Formulation PBS, pH 7.2 without preservatives and foreign proteins.
State: Azide Free
State: Lyophilized IgG fraction.
Reconstitution Method Restore by adding 1.0 ml of sterile distilled water.
Concentration lot specific
Purification Ammonium Sulphate Precipitation and Ion Exchange Chromatography.
Conjugation Unconjugated
Storage Condition Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
If a slight precipitation occurs upon storage, this should be removed by centrifugation.
Avoid repeated freezing and thawing.
Background Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme.
It Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity).
Synonyms ALD5, Aldehyde dehydrogenase [NAD(P)+] 1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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